Citação:
Results: Univariate analysis showed lower mortality in the ivermectin group (25.2% versus 15.0%, OR 0.52, 95% CI 0.29-0.96, P=.03). Mortality was also lower among 75 patients with severe pulmonary disease treated with ivermectin (38.8% vs 80.7%, OR 0.15, CI 0.05-0.47, P=.001), but there was no significant difference in successful extubation rates (36.1% vs 15.4%, OR 3.11 (0.88-11.00), p=.07). After adjustment for between-group differences and mortality risks, the mortality difference remained significant for the entire cohort (OR 0.27, CI 0.09-0.85, p=.03; HR 0.37, CI 0.19-0.71, p=.03). Conclusions and Relevance: Ivermectin was associated with lower mortality during treatment of COVID-19, especially in patients who required higher inspired oxygen or ventilatory support. These findings should be further evaluated with randomized controlled trials.
Citação:
A retrospective study of 173 COVID-19 patients treated with IVM in four Florida hospitals at a dose of 200 µg/kg yielded a 40% reduction in mortality compared with 107 controls (15.0% vs. 25.2%, p=0.03). Mortality was cut by 52% with IVM for patients having severe pulmonary disease (38.8% vs. 80.7%, p=0.001). Stabilization and then improvement over 1-2 days frequently occurred for patients who had rapidly deteriorating oxygen status.
Citação:
Researchers at University Hospital Tübingen in Germany studied the blood of 365 people, 180 of whom had had Covid-19 and 185 who hadn't.
When the researchers exposed people's blood to SARS-CoV-2, the virus that causes Covid-19, people who had had the illness already produced the strongest immune response.
But surprisingly, there was also an immune reaction in 81 per cent of the people (150) who had never had Covid-19.
This, the scientists said, was because they had already been infected with one or more of the common cold coronaviruses known to infect humans - named OC43, 229E, NL63 and HKU1 - and their immune systems cross-reacted as a result
Basicamente... Ter infecções respiratórias como gripes e coronas virus comum te ajudam a ter mais imunidade contra o covid19.