Postado originalmente por Coronavirus disease (COVID-19): COVID-19 vaccines and people living with HIV - 14 July 2021 | Q&A
Recently, a debate in the scientific literature has led to broader concerns about a potential association observed more than a decade ago between adenovirus vector-based vaccines and an increased risk of acquiring HIV infection among men who received this type of vaccine[1]. This unexpected finding was detected in two HIV vaccine trials that used adenovirus vector containing products[2],[3]. The reason for this observed HIV risk remains uncertain, although several follow-up studies have suggested a possible interference in the HIV specific vaccine response or in the CD4 cell susceptibility to HIV infection induced by this kind of vaccine[4],[5]. However, a third study using another adenovirus vector-based vaccine, conducted more recently has not reported this finding[6]. Specific studies on this topic with COVID-19 vaccines are needed. Despite these potential concerns, it is important to highlight that the benefits of all authorized COVID-19 vaccines in a pandemic context currently outweigh the potential risks. WHO will continue to monitor the situation as new data become available and SAGE recommendations will be updated accordingly.